Endocrinology and DM exam for FCPS part 1 with dr Sohrab

1. Regarding thyroid hormone - a) T3 is an inactive metabolite b) 90% of T4 bound to thyroid binding globulin c) 90% of T3 comes to conversion of T4 d) Is an essential hormone e) Mostly comes from follicular cells of thyroid

2. Patient came with you hypertension, he takes antihypertensive drug for long. Now develops 50 gynaecomastia, which drug responsible for this - a) Digoxin b) Thiazide c) Amlodipine d) Verapamil e) Spironolactone

3. Regarding insulin like growth factor - a) Its regulate blood glucose b) Its associated with growth hormone in adult individual c) It is a protein hormone d) Its acts as a insulin e) Increased blood estrogen level

4. Hypocalcaemia with increased serum PTH level - a) Acute pancreatitis b) Hypoalbuminaemia with nephrotic syndrome c) Hypomagnesemia d) CKD e) Vitamin D deficiency

5. Anti-Diabetic drug causes weight loss- a) Metformin b) DPP-4 inhibitor c) GLP-agonist d) SGLT-2 inhibitors e) Glitazones

6. Features of acromegaly are - a) Headache b) Carpal tunnel syndrome c) Acne d) Thickened skin e) Bradycardia

7. Hashimoto's thyroiditis - a) Hyperthyroidism is the cause b) Associated with other autoimmune c) free T3, T4 in serum d) Occur in male aged 30-50 years e) Painful enlargement of thyroid gland occur

8. Primary adrenocortical insufficiency produces - a) Hypoglycemia b) Hypotension c) Hypokalemia d) Metabolic acidosis e) Hypopigmentation

9. Biochemical features of primary hyperparathyroidism- a) † Serum phosphate level b) Normal serum calcium level c) Normal serum 25 (OH) D d) ↑ Serum PTH e) Serum ALP

10. Hormone acting through intracellular cytoplasmic receptor- a) Steroid b) Thyroxine c) Insulin d) Epinephrine e) PTH

11. Causes of hyper gonadotrophic hypogonadism- a) Mumps orchitis b) TB c) K linefelter's syndrome d) Turner's syndrome e) Hypopituitarism

12. Regarding congenital adrenal hyperplasia - a) 21 ß-hydroxylase deficiencies is a important cause b) ↑ ACTH secretion c) Change in Renin Activity d) May present with activity e) Autosomal dominant disorder

13. ACTH - a) It can be given for diagnostic purpose b) Secreted from adrenal cortex c) Increased secretion causes adrenal hyperplasia d) Inactivated when given orally e) Increased secretion causes Cushings syndrome

14 . Glycosylated hemoglobin- a) Give assumption of previous 3 month of glycemic status b) Useful in hypoglycemia c) Affected anemia d) Positive in 6% cases e) Enzymatic attachment of glucose to Hb

15. SIADH causes - a) Hyponatremia b) Normal blood volume c) Peripheral edema d) Cerebral edema e) Blood onmolarity

16. Growth hormone -- a) Dwarfism b) Gigantism c) Hirsutism d) Acromegaly e) Cretinism

17. In MEN-1 syndrome - a) Gastrinoma b) Prolactinoma c) Insulinoma d) Primary hyperparathyroidism vajaduding ed eit troml e) Pheochromocytoma

18. In case of turner's syndrome -- a) Elevated FSH b) Decreased LH c) Increased testosterone d) Short stature due to growth hormone deficiency e) Lack of oestrogen

19. What are the microvascular complications of DM-- a) Ischaemia b) Claudication c) TIA d) Renal failure e) vision

20. Pituitary hormones which are controlled by negative acting releasing factors from the hypothalamus are -- a) Growth hormone b) Adrenocorticotropic hormone c) Thyroid stimulating hormone d) Follicle stimulating hormone e) Prolactin

21. Type I diabetes mellitus is -- a) Accompanied by impaired B cell function b) Related to T cell mediated autoimmunity c) Not related to HLA antigen d) Associated with insulitis e) Not stress related for its development

22. Site of action of insulin include a) Adipose tissue b) Muscle c) Liver d) Kidney e) Heart

23. Macro-vascular changes in DM include-- a) Myocardial infarction b) Cataract c) Peripheral neuropathy d) Stroke e) Ischemia

24. Sulphonyureas -- a) Given in obese patients b) Given in gastctional diabetes c) Acts on B-cells d) 30% ß-cells should be normal for it's function e) Metabolism increased during taking phenobarbitone

25. Involution of thymus in adult done by - a) Adrenocortical hormone 5 b) Thyroxine c) Oestrogen d) Growth hormone e) Testosterone

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Endocrinology and DM exam for FCPS part 1 with dr Sohrab

Endocrinology and DM exam for FCPS part 1 with Dr Sohrab