General Aspects of medical practice , Genetics Exam For FCPS part 1 with dr Sohrab

Gene therapy used in following disease a) Leukaemia b) Antitrypsin deficiency c) Thalassemia d) Leukoplakia e) Erythroplakia

Option a is true
Option a is false
Option b is true
Option b is false
Option c is true
Option c is false
Option d is true
Option d is false
Option e is true
Option e is false

Autosomal dominant diseases are a) Ehler-danlos syndrome b) Myotonic dystrophy c) Osteogenesis imperfect d) Friedreich ataxia e) Spinal muscular atrophy

Feature of X linked recessive inheritance a) X-linked diseases are mostly recessive and restricted to males who carry the mutant anere b) Occasionally female carries may exhibit signs of an x-linked disease c) The gene can be transmitted from female carries to their sons d) Affected males cannot transmitted the condition to their sons e) Risk of female carrier having an affected child is 25%

Autosomal recessive conditions are a) Friedrich's ataxia b) Spinocerebellar ataxia c) Ataxia telangiectasia d) Alzheimer's disease e) Huntington's disease

Turner's syndrome is associates with a) Short stature b) Primary amenorrhea c) Deafness d) IGT e) DM

The followings are the trisomy's a) Down's syndrome b) Edward's syndrome c) Turner's syndrome d) Patau's syndrome e) Fragile X syndrome

Preventing methods in genetic disease-- a) Avoidance of consanguinity b) Pre-implantation diagnosis & genetic counseling c) Sterilization d) Maternal alpha-fetoprotein measurement e) Transabdominal chorionic villas biopsy

Cytogenic study in gene effect occurring in a) Skeletal muscle b) Bone marrow c) Blood d) Cartilage e) Nervous tissue

Clinical reasoning comprises a) Clinical skills b) Using and interprete diagnostic tests c) Doctor centered EBM d) Thinking of thinking e) Shared decision making

Clinical audit parts are -- a) Define standards b) Evaluate results c) Implement changes d) Monitor outcome e) Compare with charge

Barrier of good communication related to clinician a) Misconception b) Cognitive impairment c) Use of jargon d) Hurried approach e) Dismissive attitude

During pregnancy a) HB increase b) Thrombocytopenia c) VWF increase d) DVT e) Hemolysis

The doctor-patient relationship should encourage - a) Helping the patients and families to participate in the decision-making process b) Non-communication of complex medical information to the patients c) To provide patients with information even if they do not want to know d) The patient to take lead in determining to overall direction of care e) Guidance for the patient through the unfamiliar language and customs of clinical care

Behaviors and roles that facilitate the doctor-patient relationship are a) Clarity of speech b) Inability to criticize c) Use of jargon d) Failure to listen e) Praise and honor

Barriers to good communication in health care are a) Hurried approach by the clinician b) Use of jargon by the clinician c) Dismissive attitude of the clinician d) Cognitive impairment of the patient e) Patient's reluctance to discuss sensitive issues

Medical ethics -- a) Is concerned with conduct & competence of doctors b) Virtue ethic is concerned with characteristics of a virtuous person c) Denote logical ethics include rights & duties d) Teleological ethics is consequence of a proposed work e) Clinical ethics seals with doctors & patients

Ethical aspects of medical practice includes a) Maintenance of confidentiality b) Personal safety c) Disclosure of mistake, if any d) Personal interest e) Patient's interest

Regarding hereditary angioedema a) Mediator is Bradykinin b) Ureticaria rarely occur c) Deficiency of complement may cause d) Treatment is anti-histamine e) C4 level should be investigated

Family history is important for the following diseases а) DIC b) ITP c) NIDDM d) Albinism e) Turner's syndrome

Immune complex mediated diseases are a) Post streptococcal glomerulonephritis b) Good pasture's syndrome c) SLE d) Rheumatoid arthritis e) Polyarthritis nodes

The laboratory method of ELISA a) Can only analyses samples qualitatively b) Can detect both antigen & antibody c) Uses the enzyme horse radish peroxide d) Can use a spectrophotometer to measure the color reaction e) Is a sensitive test

Example of type III hypersensitivity a) Anaphylaxis b) SLE c) Serum sickness d) Good pasture's disease e) Glomerulonephritis

Immunoglobulin treatment is given in the following conditions a) Multiple myeloma b) GBS c) Immune thrombocytopenia d) Acute renal failure e) Pregnancy

Inflammation-- a) Release of insulin b) Hypertension c) Hypothalamic change in temperature set point d) Associated with anorexia & confusion e) Impair release of catecholamine from adrenal cortex

Live attenuated vaccine a) Pertussis b) Yellow fever c) Influenza d) Pneumo coccus e) HBV